Background : PPN(Polyperipheral neruopathy), one of most common complications, has diverse clinical feattaes and many efforts was tried to diagnosis amd evaluate PPN quantitatively. Among them,
NCV(nerve conduction velocity) is recognized as most reliable test. but practically, its clinical application has limitation because of technical difficulty and high cost. So, We examed QST(quantitative sensory test) and NCV in NIDDM patients and evaluated usefulness of QST as diagnostic test and analyzed the correlation betwen NCV and QST.
Methods : In 93 NIDDM patients, we examined clinical characteristics(HbAlc, Albumin excretion tate(AER), serum lipid profile), NCV test and QST. We classified them into 2 group according to the result of NCV and compared the QST results in 2 groups.
Results :
1) In group with PPN, the average of age, duration, HbAlc, AER were higher than the other.(p<0.0$) As the value of age, duration,HbAlc, AER was increased, the risk of PPN in MDDM pts was increased(p<0.05).
2) The sensory thresholds in QST had significant difference in 2 groups(p<0.05).
3) The amplitude in NCV had negative correlation with the s<;nsory threshold in QST(-0.089 to -0.433).
4) The correlat;on value of sensory threshold in QST with conduction velocity was higher than amplitude in NCV, and higher in lower limb than in uF~per limb.
5) The value of conduction velocity was more correlated with 1 point test value than 2 point.
Conclusion : Our results suggest that there is low cotrf;latian witty NCV and QST, but QST can be used as a useful screening and follow-up test in diagtosis of diabetic PPN instead of NCV.
|